A Practical Guide to Getting Your Hands on Tretinoin—the Fastest-Acting, Strongest Form of Retinol

If you’re into skincare, you likely know all about the incredible powers of vitamin A—commonly referred to in the industry as retinoids, retinols and retinals. They are the only scientifically-proven way to reduce the signs of ageing, as they work on a cellular level, increasing cell turnover, stimulating the production of collagen and reducing inflammation. This, by and by, reduces the appearance of fine lines and wrinkles, helps treat and prevent acne, fades dark marks and improves the texture and firmness of skin.

Today, there are hundreds of retinoids on the market, but dermatologists have long crowned tretinoin as the gold standard. This prescription-only product is the fastest-acting and strongest form of retinoid we have today, thanks to the fact that it already comes in the active form of vitamin A. As consultant dermatologist Dr Derrick Phillips explains: “Both retinol and tretinoin are forms of vitamin A, but they work a little differently. Retinol needs to be converted by the skin into Retinaldehyde (Retinal) and then into tretinoin before it becomes active. Tretinoin, on the other hand, is already in its active form, so your skin can use it immediately. That’s why tretinoin is more potent and effective, while retinol tends to be gentler but slower-acting.”